Gut microbiota as a new target for anticancer therapy: from mechanism to means of regulation
Jiaao Sun, Shiyan Song, Jiahua Liu, Feng Chen, Xiaorui Li, Guangzhen Wu
Abstract
In order to decipher the relationship between gut microbiota imbalance and cancer, this paper reviewed the role of intestinal microbiota in anticancer therapy and related mechanisms, discussed the current research status of gut microbiota as a biomarker of cancer, and finally summarized the reasonable means of regulating gut microbiota to assist cancer therapy. Overall, our study reveals that the gut microbiota can serve as a potential target for improving cancer management.
Topics & Concepts
Gut floraMechanism (biology)CancerCancer therapyBiomarkerDECIPHERBiologyDiagnostic biomarkerBioinformaticsComputational biologyMedicineImmunologyGeneticsPhilosophyEpistemologyGut microbiota and healthClostridium difficile and Clostridium perfringens researchPancreatic and Hepatic Oncology Research