Inhibition of SerpinB9 to enhance granzyme B-based tumor therapy by using a modified biomimetic nanoplatform with a cascade strategy
Ran Han, Luting Yu, Chenxuan Zhao, Ying Li, Yuying Ma, Yuewen Zhai, Zhiyu Qian, Yueqing Gu, Siwen Li
Topics & Concepts
Granzyme BPhotothermal therapyNanocarriersCancer researchTumor microenvironmentImmunotherapyDownregulation and upregulationMicrovesiclesImmune systemTargeted therapyMelanomaMaterials scienceImmunologyCancerMedicineChemistryT cellDrug deliveryNanotechnologyTumor cellsmicroRNAInternal medicineBiochemistryGeneExtracellular vesicles in diseaseImmune cells in cancerPhagocytosis and Immune Regulation