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Mechanisms of resistance to CAR-T cell immunotherapy: Insights from a mathematical model

Daniela Silva Santurio, Emanuelle Arantes Paixão, Luciana Rodrigues Carvalho Barros, Regina C. Almeida, Artur C. Fassoni

2023Applied Mathematical Modelling12 citationsDOI

Topics & Concepts

Chimeric antigen receptorImmunotherapyAntigenImmunologyCytotoxicityCellMechanism (biology)Cell therapyCancer researchBiologyMedicineComputational biologyImmune systemGeneticsIn vitroPhysicsQuantum mechanicsCAR-T cell therapy researchImmune Cell Function and Interaction