Selection of appropriate non-clinical animal models to ensure translatability of novel AAV-gene therapies to the clinic
Mark Singh, Andrëw G. Brööks, Parto Toofan, Keith McLuckie
Topics & Concepts
Genetic enhancementBiologyTransgeneAdeno-associated virusVector (molecular biology)Computational biologyGene deliverySelection (genetic algorithm)Viral vectorGeneBioinformaticsClinical trialRecombinant DNAVirologyGeneticsComputer scienceArtificial intelligenceVirus-based gene therapy researchCRISPR and Genetic EngineeringViral Infectious Diseases and Gene Expression in Insects