COVID-19 vaccine and autoimmunity. A new case of autoimmune hepatitis and review of the literature
Laura Camacho-Domínguez, Yhojan Rodríguez, Fernando Polo, Juan Carlos Restrepo, Elizabeth Zapata, Manuel Rojas, Juan‐Manuel Anaya
Abstract
Autoimmunity following COVID-19 vaccination has been reported. Herein, a 79-year-old man with clinical and immunological features of autoimmune hepatitis type 1 after ChAdOx1 nCoV-19 vaccination is presented. Clinical manifestations rapidly remitted after the instauration of immunomodulatory management. This case, together with a comprehensive review of the literature, illustrates the association between COVID-19 vaccines and the development of autoimmune conditions.
Topics & Concepts
AutoimmunityCoronavirus disease 2019 (COVID-19)MedicineImmunologyVaccinationAutoimmune hepatitis2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyHepatitisImmune systemDiseasePathologyInfectious disease (medical specialty)OutbreakLiver Diseases and ImmunitySARS-CoV-2 and COVID-19 ResearchHepatitis Viruses Studies and Epidemiology