Structural basis for inhibition of the cardiac sodium channel by the atypical antiarrhythmic drug ranolazine
Michael J. Lenaeus, Tamer M. Gamal El-Din, Lige Tonggu, Ning Zheng, William A. Catterall
Topics & Concepts
RanolazineSodium channelPharmacologyCardiac electrophysiologyChemistryElectrophysiologyCardiac action potentialDrugDepolarizationCardiologyMedicineInternal medicineSodiumRepolarizationOrganic chemistryCardiac electrophysiology and arrhythmiasIon channel regulation and functionElectrochemical Analysis and Applications