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Enhancing the oral bioavailability of simvastatin with silica-lipid hybrid particles: The effect of supersaturation and silica geometry

Tahlia R. Meola, Hayley B. Schultz, Karl Peressin, Clive A. Prestidge

2020European Journal of Pharmaceutical Sciences36 citationsDOI

Topics & Concepts

BioavailabilitySupersaturationSimvastatinSolubilityIn vivoChromatographyMaterials sciencePharmacokineticsChemistryParticle sizeDissolutionFumed silicaSpray dryingChemical engineeringOrganic chemistryPharmacologyBiotechnologyPhysical chemistryBiologyEngineeringMedicineDrug Solubulity and Delivery SystemsDrug Transport and Resistance MechanismsAdvanced Drug Delivery Systems
Enhancing the oral bioavailability of simvastatin with silica-lipid hybrid particles: The effect of supersaturation and silica geometry | Litcius