Litcius/Paper detail

Enhanced bioactivity of ZnO nanoparticles—an antimicrobial study

Nagarajan Padmavathy, R. Vijayaraghavan

2008Science and Technology of Advanced Materials1,660 citationsDOIOpen Access PDF

Abstract

and NaOH. The products were characterized by x-ray diffraction (XRD) analysis, transmission electron microscopy (TEM) and photoluminescence (PL) spectroscopy. Bacteriological tests such as minimum inhibitory concentration (MIC) and disk diffusion were performed in Luria-Bertani and nutrient agar media on solid agar plates and in liquid broth systems using different concentrations of ZnO by a standard microbial method for the first time. Our bacteriological study showed the enhanced biocidal activity of ZnO nanoparticles compared with bulk ZnO in repeated experiments. This demonstrated that the bactericidal efficacy of ZnO nanoparticles increases with decreasing particle size. It is proposed that both the abrasiveness and the surface oxygen species of ZnO nanoparticles promote the biocidal properties of ZnO nanoparticles.

Topics & Concepts

NanoparticleZincMaterials scienceParticle sizeTransmission electron microscopyAntibacterial activityAgarPrecipitationNuclear chemistryChemical engineeringPhotoluminescenceParticle (ecology)NanotechnologyChemistryBacteriaMetallurgyOceanographyMeteorologyOptoelectronicsEngineeringPhysicsGeologyBiologyGeneticsZnO doping and propertiesElectronic and Structural Properties of OxidesNanoparticles: synthesis and applications