Macrophage correlates with immunophenotype and predicts anti-PD-L1 response of urothelial cancer
Dongqiang Zeng, Zilan Ye, Jiani Wu, Rui Zhou, Xinxiang Fan, Gaofeng Wang, Yiqiang Huang, Jianhua Wu, Huiying Sun, Miaohong Wang, Jianping Bin, Yulin Liao, Nailin Li, Min Shi, Wangjun Liao
Abstract
mutations may be promising strategies for synergy with anti-PD-L1 treatments and may help prolong the clinical survival of patients with mUC.
Topics & Concepts
ImmunophenotypingImmune checkpointImmune systemTranscriptomeCancer researchImmunotherapyCD8BiomarkerTumor microenvironmentMedicineBiologyImmunologyOncologyGene expressionFlow cytometryGeneGeneticsBladder and Urothelial Cancer TreatmentsEpigenetics and DNA MethylationFerroptosis and cancer prognosis