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A clinician's guide to cutaneous T-cell lymphoma presenting as recalcitrant eczematous dermatitis in adults

Sarah Semaan, Mary Kathryn Abel, Jodie Raffi, Jenny E. Murase

2021International Journal of Women’s Dermatology20 citationsDOIOpen Access PDF

Abstract

Cutaneous T-cell lymphoma (CTCL) encompasses a group of low-grade, non-Hodgkin lymphoma, including mycosis fungoides and Sézary syndrome. Diagnosis of CTCL can be challenging given the prolonged, gradual onset and shared characteristics with many benign inflammatory skin diseases. In this case series, we describe four unique cases of patients with chronic, recalcitrant eczematous dermatitis who presented for a patch-test consultation and were ultimately diagnosed with CTCL. In particular, we highlight clinical pearls to aid in distinguishing CTCL from inflammatory dermatoses and describe the diagnostic strategy to help dermatologists arrive at the diagnosis of CTCL at earlier stages of the disease.

Topics & Concepts

Mycosis fungoidesDermatologyEczematous dermatitisMedicineCutaneous lymphomaCutaneous T-cell lymphomaLymphomaDiseasePathologyCutaneous lymphoproliferative disorders researchNail Diseases and TreatmentsContact Dermatitis and Allergies
A clinician's guide to cutaneous T-cell lymphoma presenting as recalcitrant eczematous dermatitis in adults | Litcius