Pathological, Clinicopathological and Molecular Investigations on Chickens Experimentally Infected with Avian Leucosis Virus Type J
Ahmed Fotouh, Hamdy Soufy, El-Begawey M.B, Soad M. Nasr
Abstract
A vian retroviruses have been a major cause of mortality in poultry (Wang et al., 2017).These viruses, generally referred to as avian leucosis viruses (ALV), mainly induce leucosis affecting the various hemopoietic cells.The virus infection spreads by both vertical and horizontal transmission (Gao et al., 2012).Avian leucosis viruses of chickens are classified into types (A, B, C, D, E, and J) on the basis of interaction between virus specific cell receptors and virus envelop glycoprotein (Payne and Nair, 2012).Although avian leucosis virus (ALV) is capable of inducing a variety of neoplasms, lymphoid leucosis is the most common naturally occurring B-cell lymphoma caused by ALV.In Egypt, the diagnosis of ALV infection is based on gross pathological lesions and antibody titer in imported 21