Antibody–Drug Conjugates for Immunology
Peter S. Dragovich
Abstract
The application of antibody-drug conjugates (ADCs) to fields outside of oncology is increasing but is still relatively uncommon. A recent publication describes the conjugation of glucocorticoid receptor modulators to antibodies as a means of improving the separation between desired anti-inflammatory activity and unwanted systemic side effects.
Topics & Concepts
ChemistryDrugAntibodyConjugatePharmacologyGlucocorticoid receptorAntibody-drug conjugateImmunologyReceptorMonoclonal antibodyBiochemistryMedicineMathematicsMathematical analysisHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchEstrogen and related hormone effects