Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer
Soumyadip Das, Arun Pandian Chandrasekaran, Bharathi Suresh, Saba Haq, Jae-Hyeok Kang, Su‐Jae Lee, Jaewon Kim, Jaesang Kim, Sanghyuk Lee, Seokjoong Kim, Kye-Seong Kim, Suresh Ramakrishna
Topics & Concepts
Deubiquitinating enzymeCDC25ABiologySubfamilyKnockout mouseCell cycleGenome instabilityCancer researchCancerGene knockoutUbiquitinGeneDNA damageCell biologyGeneticsComputational biologyCell cycle checkpointDNAUbiquitin and proteasome pathwaysCancer-related Molecular PathwaysDNA Repair Mechanisms