Deciphering the prognostic significance of anoikis-related lncRNAs in invasive breast cancer: from comprehensive bioinformatics analysis to functional experimental validation.
Wenge Dong, Jiejing Li, Zhigang Zhuang
Abstract
, significantly impeded the proliferation and migration, as well as possibly the anoikis resistance of breast cancer cells. These findings highlight the potential of the ARL signature as a robust prognostic tool and a promising basis for personalized IBC treatment strategies.
Topics & Concepts
Breast cancerAnoikisOncologyBiologyDiseaseTranscriptomeImmunotherapyTumour heterogeneityComputational biologyLong non-coding RNABioinformaticsMedicineCancerInternal medicineMetastasisGeneRNAGene expressionGeneticsCancer-related molecular mechanisms researchFerroptosis and cancer prognosisCircular RNAs in diseases