ZFPM2-AS1 transcriptionally mediated by STAT1 regulates thyroid cancer cell growth, migration and invasion via miR-515-5p/TUSC3
Ruizhen Ren, Yuanna Du, Xing Niu, Rukun Zang
Abstract
ZFPM2-AS1 acted as an oncogene in thyroid cancer, which was transcriptionally mediated by STAT1. Furthermore, ZFPM2-AS1 weakened the inhibitory effect of miR-515-5p on TUSC3. Thus, ZFPM2-AS1 could be an underlying biomarker for thyroid cancer.
Topics & Concepts
Cancer researchThyroid cancerSTAT1ThyroidCancerCell migrationBiologyMedicineCellCell biologyInternal medicineSignal transductionGeneticsCancer-related molecular mechanisms research