Underground railway particulate matter and susceptibility to pneumococcal infection
Lisa Miyashita, Rebecca K. Shears, Gary Foley, Sean Semple, Aras Kadioglu, Jonathan Grigg
Abstract
BACKGROUND: on; i) pneumococcal adhesion to airway cells, and ii) susceptibility to pneumococcal disease. METHODS: . FINDINGS: -exposed mice with CV3988 reduced blood CFU. INTERPRETATION: increases pneumococcal adhesion to airway cells and susceptibility to invasive disease in mice. FUNDING: The Medical College of Saint Bartholomew's Hospital Trust, and the UK Medical Research Council Programme Grant (MR/P011284/1).
Topics & Concepts
ImmunologyFlow cytometryMedicineReceptor expressionStreptococcus pneumoniaeReceptorMicrobiologyBiologyInternal medicineAntibioticsAir Quality and Health ImpactsChronic Obstructive Pulmonary Disease (COPD) ResearchOccupational exposure and asthma