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Inferring thalamocortical monosynaptic connectivity in vivo

Yi Juin Liew, Aurélie Pala, Clarissa J. Whitmire, William Stoy, Craig R. Forest, Garrett B. Stanley

2021Journal of Neurophysiology27 citationsDOIOpen Access PDF

Abstract

Despite the fact that all brain function relies on the long-range transfer of information across different regions, the tools enabling us to measure connectivity across brain structures are lacking. Here, we provide a statistical framework for identifying and assessing potential monosynaptic connectivity across neuronal circuits from population spiking activity that generalizes to large-scale recording technologies that will help us to better understand the signaling within networks that underlies perception and behavior.

Topics & Concepts

NeuroscienceSomatosensory systemComputer scienceConnectomicsNerve netConnectomePopulationSensory systemThalamusFunctional connectivityBiologyMedicineEnvironmental healthNeural dynamics and brain functionNeuroscience and Neural EngineeringNeuroscience and Neuropharmacology Research
Inferring thalamocortical monosynaptic connectivity in vivo | Litcius