Autophagy Regulates Whitefly-Symbiont Metabolic Interactions
Yan-Bin Wang, Ce Li, Jin-Yang Yan, Tian-Yu Wang, Ya-Lin Yao, Fei-Rong Ren, Jun-Bo Luan
Abstract
. Hamiltonella" alleviate autophagy by activating the TOR (target of rapamycin) pathway through providing essential nutrients. Therefore, we demonstrate that autophagy plays a critical role in regulating the metabolic interactions between the whitefly and two intracellular symbionts. This study also provides insight into the cellular basis of bacteriocyte evolution and symbiosis persistence in the whitefly. The mechanisms underlying the role of autophagy in whitefly symbiosis could be widespread in many insect nutritional symbioses. These findings provide a new avenue for whitefly control via regulating autophagy in the future.
Topics & Concepts
BiologyAutophagyCell biologyWhiteflyGene silencingMetabolic pathwayHost (biology)SymbiosisRNA interferenceIntracellularMetabolismBiochemistryAmino acidSignal transductionPsychological repressionB vitaminsBacteriaVitaminMechanism (biology)RegulatorGreenhouse whiteflyInsectInsect symbiosis and bacterial influencesStudies on Chitinases and ChitosanasesForensic Entomology and Diptera Studies