Recent advances in the synthesis of pyrido[1,2-<i>a</i>]indoles
Yunxin Yao, Mouâd Alami, Abdallah Hamzé, Olivier Provot
Abstract
The pyrido[1,2-a]indole unit found in many organic compounds such as natural products, pharmaceuticals, and materials, has intensively stimulated the research of new synthetic pathways giving access to this heterocyclic nucleus in very recent years. In this review, the synthesis of pyrido[1,2-a]indoles will be divided into two parts, which concern accesses to this skeleton using or not metal catalysis.
Topics & Concepts
Indole testComputer scienceChemistryStereochemistryCatalytic C–H Functionalization MethodsAxial and Atropisomeric Chirality SynthesisSynthesis and Reactivity of Heterocycles