Application of the Threshold of Toxicological Concern (TTC) in Food Safety: Challenges and Opportunities
Rositsa Serafimova, Tamara Čoja, George E.N. Kass
Abstract
studies performed on experimental animals. The nature and amount of data required to carry out a risk assessment is generally stipulated either in the different food legislations or in sectoral guidance documents. However, there are still cases where no or only limited experimental data are available or not specified by law, for example for contaminants or for some minor metabolites from active substances in plant protection products. For such cases, the Threshold of Toxicological Concern (TTC) can be applied. This review explores the use of the TTC approach in food safety in the European Union, in relation to the different food sectors, legal requirements and future opportunities.
Topics & Concepts
European unionFood safetyRisk analysis (engineering)Risk assessmentBusinessBiotechnologyToxicologyComputer scienceBiologyComputer securityFood scienceInternational tradeAgricultural safety and regulationsEffects and risks of endocrine disrupting chemicalsAnimal testing and alternatives