One-pot strategy for thiazole tethered 7-ethoxy quinoline hybrids: Synthesis and potential antimicrobial agents as dihydrofolate reductase (DHFR) inhibitors with molecular docking study
Yousry A. Ammar, Sondos M. A. Abd El‐Hafez, Sadia A. Hessein, Abeer M. Ali, Ahmed A. Askar, Ahmed Ragab
Topics & Concepts
ChemistryThiazoleDihydrofolate reductaseAntimicrobialQuinolineDocking (animal)CiprofloxacinNorfloxacinActive siteStereochemistryEnzymeCombinatorial chemistryAntibioticsBiochemistryOrganic chemistryMedicineNursingSynthesis and biological activityCancer therapeutics and mechanismsSynthesis and Biological Evaluation