Liraglutide Attenuates Myocardial Ischemia/Reperfusion Injury Through the Inhibition of Necroptosis by Activating GLP-1R/PI3K/Akt Pathway
Gang Zhou, Hui Wu, Jian Yang, Ming Ye, Di Liu, Yunzhao Li, Dong Zhang, Jing Zhang, Qingzhuo Yang, Yanfang Liu
Topics & Concepts
NecroptosisLiraglutideProtein kinase BMedicineLY294002PI3K/AKT/mTOR pathwayReperfusion injuryPharmacologyProgrammed cell deathCardioprotectionIschemiaInternal medicineChemistryEndocrinologyApoptosisBiochemistryDiabetes mellitusType 2 diabetesCardiac Ischemia and ReperfusionHyperglycemia and glycemic control in critically ill and hospitalized patientsCell death mechanisms and regulation