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Design, synthesis and enzymatic inhibition evaluation of novel 4-hydroxy Pd–C-Ⅲ derivatives as α-glucosidase and PTP1B dual-target inhibitors

Wei Yang, Jiyu Chen, Zhiyun Peng, Guangcheng Wang

2024European Journal of Medicinal Chemistry12 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryEnzymeStereochemistryEnzyme inhibitorChemical synthesisBiochemistryDual (grammatical number)Combinatorial chemistryIn vitroArtLiteratureProtein Tyrosine PhosphatasesCarbohydrate Chemistry and SynthesisBioactive Compounds and Antitumor Agents
Design, synthesis and enzymatic inhibition evaluation of novel 4-hydroxy Pd–C-Ⅲ derivatives as α-glucosidase and PTP1B dual-target inhibitors | Litcius