Oligonucleotides and the COVID-19 Pandemic: A Perspective
John J. Rossi, Daniel Rossi
Abstract
The present global health emergency involving the emergence and rapid spread of a novel coronavirus has prompted the world scientific community to consider how it can help to fight this growing viral pandemic. With few safe and effective drugs available to combat this threat to humanity and the normal functioning of our society, the oligonucleotide research community is uniquely positioned to apply its technology and expertise to help alleviate the crisis, thanks to its capacity for rational drug design, swift development cycles, and pursuing targets undruggable by conventional treatment strategies.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Pandemic2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)HumanityPerspective (graphical)Drug developmentRisk analysis (engineering)Political scienceBusinessVirologyComputer scienceBiologyMedicineDrugInfectious disease (medical specialty)LawPharmacologyDiseaseArtificial intelligencePathologyOutbreakSARS-CoV-2 and COVID-19 Researchinterferon and immune responsesRNA Interference and Gene Delivery