Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer
Yuting Zhou, Xingwei Xu, Fei Wang, Huan He, Guowei Gong, Xiong Li, Baohui Qi
Topics & Concepts
ChemistryQuinolineIC50CabozantinibKinasePharmacologyCell growthLead compoundStereochemistryBiochemistryIn vitroCancerInternal medicineBiologyMedicineOrganic chemistryPI3K/AKT/mTOR signaling in cancerSynthesis and biological activityBiochemical and Molecular Research