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RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia

Michael McMillan, Nicolás Gómez, Caroline Hsieh, Michael E. Bekier, Xingli Li, Roberto Miguez, Elizabeth M.H. Tank, Sami J. Barmada

2023Molecular Cell108 citationsDOIOpen Access PDF

Topics & Concepts

Amyotrophic lateral sclerosisFrontotemporal dementiaBiologyPathogenesisRNA-binding proteinMethylationDiseaseRNA methylationRNAC9orf72NeuroscienceGeneticsDementiaGeneImmunologyPathologyMethyltransferaseMedicineRNA modifications and cancerRNA Research and SplicingNeurogenetic and Muscular Disorders Research
RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia | Litcius