Nickel-catalyzed alkoxycarbonylation of aryl iodides with 1 atm CO
Ning Liu, Xianqing Wu, Chenglong Wang, Jingping Qü, Yifeng Chen
Abstract
A nickel-catalyzed alkoxycarbonylation of aromatic iodides with alcohols under atmospheric pressure of carbon monoxide is presented here. This operationally simple protocol allows the facile synthesis of (hetero)aromatic esters, exhibiting broad substrate scope with excellent functional group tolerance. Various primary and secondary aliphatic alcohols as well as phenols are suitable for this transformation.
Topics & Concepts
ArylCatalysisNickelChemistryPrimary (astronomy)PhenolsFunctional groupSubstrate (aquarium)Organic chemistryCarbon monoxideCombinatorial chemistryAlkylAstronomyOceanographyGeologyPolymerPhysicsCatalytic Cross-Coupling ReactionsChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods