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Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathway

Christian Jacoby, Kaylie Scorza, L. Ecker, Paola Nol Bernardino, Alexander S. Little, Mary McMillin, Ramanujam Ramaswamy, Anitha Sundararajan, Ashley M. Sidebottom, Huaiying Lin, Keith Dufault‐Thompson, Brantley Hall, Xiaofang Jiang, S.H. Light

2025Cell Host & Microbe11 citationsDOIOpen Access PDF

Topics & Concepts

BiologySteroidHormoneSteroid hormoneBacteriaMicrobiomeGut floraMicrobial metabolismMicrobiologyBiochemistryMetabolismTranscriptomeAnabolismEnzymeHost (biology)Gut bacteriaGlucocorticoidReductaseMetabolic pathwayCatabolismPeptide hormoneClostridiumGut microbiota and healthSteroid Chemistry and BiochemistryMetabolism and Genetic Disorders
Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathway | Litcius