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Green Synthesis and Antibacterial Activity of Ag/Fe2O3 Nanocomposite Using Buddleja lindleyana Extract

Fatimah A. M. Al‐Zahrani, Salem S. Salem, Huda A. Al‐Ghamdi, Laila M. Nhari, Long Lin, Reda M. El‐Shishtawy

2022Bioengineering89 citationsDOIOpen Access PDF

Abstract

In the study reported in this manuscript, silver/iron oxide nanocomposites (Ag/Fe2O3) were phytosynthesized using the extract of Buddleja lindleyana via a green, economical and eco-friendly strategy. The biosynthesized Ag/Fe2O3 nanocomposites were characterized using UV-Vis spectrophotometry, FTIR, XRD, TEM, DLS and SEM-EDX analyses. The particulates showed a triangular and spherical morphology having sizes between 25 and 174 nm. FTIR studies on the nanoparticles showed functional groups corresponding to organic metabolites, which reduce and stabilize the Ag/Fe2O3 nanocomposite. The antimicrobial efficacy of the phytosynthesized Ag/Fe2O3 against bacterial pathogens was assessed. In addition, Ag/Fe2O3 exhibited broad spectrum activities against B. subtilis, S. aureus, E. coli, and P. aeruginosa with inhibition zones of 23.4 ± 0.75, 22.3 ± 0.57, 20.8 ± 1.6, and 19.5 ± 0.5 mm, respectively. The Ag/Fe2O3 composites obtained showed promising antibacterial action against human bacterial pathogens (S. aureus, E. coli, B. subtilis and P. aeruginosa), making them candidates for medical applications.

Topics & Concepts

NanocompositeAntibacterial activityFourier transform infrared spectroscopyNuclear chemistryAntimicrobialSilver nanoparticleChemistryMaterials scienceNanoparticleMicrobiologyBacteriaNanotechnologyBiologyChemical engineeringOrganic chemistryGeneticsEngineeringNanoparticles: synthesis and applicationsMoringa oleifera research and applicationsPhytochemistry and Bioactivity Studies