In vitro and in silico evaluation of new thieno[2,3-d]pyrimidines as anti-cancer agents and apoptosis inducers targeting VEGFR-2
Souad A. El‐Metwally, Abdelrahman A. Abuelkhir, Hazem Elkady, Mohammed S. Taghour, Ibrahim M. Ibrahim, Dalal Z. Husein, Aisha A. Alsfouk, Ahlam Sultan, Ahmed Ismail, Samy Y. Elkhawaga, Eslam B. Elkaeed, Ahmed M. Metwaly, Ibrahim H. Eissa
Topics & Concepts
ApoptosisPyrimidineChemistryCancer cellIn vitroCell cycleIC50MCF-7In silicoStereochemistryCancerCell cultureCancer researchBiochemistryBiologyGeneticsGeneHuman breastBioactive Compounds and Antitumor AgentsSynthesis and biological activityCancer Mechanisms and Therapy