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Postpartum microvascular functional alterations following severe preeclampsia

Logan C. Barr, Jessica Pudwell, Graeme N. Smith

2021American Journal of Physiology-Heart and Circulatory Physiology21 citationsDOI

Abstract

We examine maternal microvascular function after preeclampsia, identifying heightened endothelium-dependent and endothelium-independent microvascular reactivity following severe disease. Our study represents a noteworthy addition to the existing literature with the use of a novel imaging modality, vascular perturbation, postpartum time point, and patient population with differentiation of preeclampsia into severe and nonsevere subtypes. These results represent a novel addition to the growing clinical and academic understanding of maternal health outcomes following preeclampsia.

Topics & Concepts

PreeclampsiaMedicineEndotheliumPopulationDiseasePregnancyObstetricsInternal medicineCardiologyBiologyGeneticsEnvironmental healthPregnancy and preeclampsia studiesBirth, Development, and HealthGestational Diabetes Research and Management
Postpartum microvascular functional alterations following severe preeclampsia | Litcius