Ring finger protein 6 enhances chemo-resistance by transcriptionally activating proliferating cell nuclear antigen expression and attenuating DNA damage in lung adenocarcinoma
Yile Sun, Hongmiao Sun, Yuwen Qi, Mengqiao Pan, Na An, Xuejiao Leng, Yun Liu, Zhiwei Chen
Topics & Concepts
Proliferating cell nuclear antigenGene knockdownBiologyMolecular biologyChromatin immunoprecipitationCancer researchCisplatinDNA repairA549 cellPromoterChromatinCell biologyGene expressionCell growthCellDNAGeneBiochemistryGeneticsChemotherapyGenomics and Chromatin DynamicsEpigenetics and DNA MethylationRNA modifications and cancer