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Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism

Benedikt Bauer, Iain F. Davidson, Daniel Canena, Gordana Wutz, Wen Tang, Gabriele Litos, Sabrina Horn, Peter Hinterdorfer, Jan‐Michael Peters

2021Cell169 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCohesinClampMechanism (biology)DNAGeneticsSwingExtrusionLoop (graph theory)Cell biologyBiophysicsChromatinPhysicsEngineeringCombinatoricsAcousticsMaterials scienceMechanical engineeringMathematicsMetallurgyQuantum mechanicsClampingGenomics and Chromatin DynamicsDNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism | Litcius