Rapid resolution of widespread cutaneous lichen planus and generalized pruritus in an elderly patient following treatment with dupilumab
Soroush Kazemi, Morgan Murphrey, Jason E. Hawkes
Abstract
Lichen planus (LP) is a rare inflammatory disease that affects <1% of the population and is most common in middle-aged adults.1 Classically manifesting as violaceous, polygonal, flat-topped, and pruritic papules or plaques on the skin, LP has a pleiomorphic presentation and may involve the hair, nails, or mucosal tissues.2 Pruritus is a common symptom of LP and several disease associations have been described including trauma, medications, hepatitis infection, and mucosal exposure to dental restorative materials.
Topics & Concepts
MedicineDermatologyDupilumabDiseasePopulationPathologyAtopic dermatitisEnvironmental healthOral Health Pathology and TreatmentAutoimmune Bullous Skin DiseasesDermatology and Skin Diseases