Design of Bio-Artificial Liver Organ
Emin Taner Elmas
Abstract
This article introduces a project to be developed to manufacture an artificial liver and the name of the project is “Design of Bio-artificial Liver Organ”. The main goal of the project is to make a liver by making use of bionic materials, electronic systems and mechanical systems, and incorporating mechatronics knowledge. To improve the quality of life of liver patients and restore their health will be the ultimate target. In addition, the scientific and technical studies to be carried out on this subject will contribute to the enrichment of the literature on the subject and will also be beneficial for scientific and technical progress. In our country, there are 14 million people with fatty liver problems and 2 million with hepatitis and liver cancer. Therefore, such a large population related to the liver experiences serious health problems such as liver failure. Undoubtedly, the liver is of vital importance like other organs, but the difference of the liver from other organs is that it performs many comprehensive functions such as storage, regulation, synthesis and destruction. These features make the liver incredible and unattainable. We are a little far away from making an exact liver with the knowledge we currently have and the materials we can use. By the help of a bio-artificial liver organ, it is aimed to establish systems that can perform several functions of this distinguished organ that has more than one function [1-31]. The operation principle of the system of Bio-artificial Liver Organ shall be as follows: The albumin level in the blood connected to the dialysis machine is checked. The filtration process consists of a complex carbonaceous circuit. The dialysis machine vacuums the blood and draws it to the cleaning filter. Albumin separated from the patient’s blood is passed through two special adsorbents and toxins bound to albumin are removed. Toxins formed by watersoluble molecules with low and medium molecular weights are removed from the patient’s blood by hemodialysis performed in the dialysis circuit. The blood separated from the filtered albumin is adjusted by a pressure adjustment device and enters the patient’s body in a clean state. Albumin contains toxic substances that are harmful to the body [1-31].