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Introducing Phenalenyl-Based Organic Lewis Acid as a Photocatalyst to Facilitate Oxidative Azolation of Unactivated Arenes

Partha Pratim Sen, Sudipta Raha Roy

2023Organic Letters29 citationsDOI

Abstract

By revealing the robust photooxidant properties of phenalenyl-based organic Lewis acid, we have introduced this moiety as an effective organophotocatalyst for the oxidative azolation of unactivated and feedstock arenes. In addition to its tolerance for various functional groups and scalability, this photocatalyst was shown to be promising for the defluorinative azolation of fluoroarenes.

Topics & Concepts

ChemistryMoietyLewis acids and basesPhotocatalysisOxidative phosphorylationOrganic chemistryCombinatorial chemistryRaw materialCatalysisBiochemistryFluorine in Organic ChemistryRadical Photochemical ReactionsCatalytic C–H Functionalization Methods
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