Design, synthesis, and biological evaluation of BRD4 degraders
Mengyuan Ding, Ying-Ying Shao, Danwen Sun, Suorina Meng, Yi Zang, Yubo Zhou, Jia Li, Wei Lü, Shulei Zhu
Topics & Concepts
BromodomainBRD4EpigeneticsChemistryCancer researchProtein degradationCell biologyCell cultureBiochemistryBiologyGeneGeneticsProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways