Oral Azacitidine (CC-486) for the Treatment of Myeloid Malignancies
Guillermo Garcia‐Manero, Hartmut Döhner, Andrew H. Wei, Ignazia La Torre, Barry Skikne, C.L. Beach, Valeria Santini
Topics & Concepts
MedicineAzacitidineMyelodysplastic syndromesInternal medicineClinical trialOncologyMyeloid leukemiaMaintenance therapyHypomethylating agentRefractory (planetary science)Randomized controlled trialPharmacodynamicsDecitabineCombination therapyDosingChemotherapyPharmacokineticsBone marrowDNA methylationAstrobiologyChemistryBiochemistryGene expressionPhysicsGeneAcute Myeloid Leukemia ResearchHistone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation