Micronuclei as biomarkers of DNA damage, aneuploidy, inducers of chromosomal hypermutation and as sources of pro-inflammatory DNA in humans
Michael Fenech, Siegfried Knasmueller, Claudia Bolognesi, Nina Holland, Stefano Bonassi, Micheline Kirsch‐Volders
Topics & Concepts
Micronucleus testGenome instabilityChromosome instabilityDNA damageBiologyMicronucleusAneuploidyMitosisBinucleated cellsChromatinChromosomal fragile siteChromothripsisCentromereGeneticsChromosomeCell biologyMolecular biologyDNAChemistryGeneOrganic chemistryToxicityImmunotherapy and Immune Responsesinterferon and immune responsesCRISPR and Genetic Engineering