Prevention and management of cutaneous immune‐related adverse events: <scp>EADV</scp> Task Force statement
Davide Fattore, Zoé Apalla, Azael Freites‐Martínez, Nello Tommasino, Vasiliki Nikolaou, Giuseppe Lauletta, Ariadna Ortiz‐Brugués, Pietro Sollena, Michela Starace, Nuno Gomes, Dimitra Koumaki, Émmanuelle Vigarios, Lukas Kraehenbuehl, Katerina Grafanaki, Maddalena Napolitano, V. Sibaud
Abstract
Cancer immunotherapy, particularly immune checkpoint inhibitors (ICI), has revolutionized oncology treatment by leveraging the immune system to recognize and eliminate cancer cells. However, despite its efficacy, immunotherapy may induce immune-related adverse events (irAEs), including dermatological events, that can range from mild rashes to severe life-threatening conditions such as toxic epidermal necrolysis. This paper aims to explore and analyse the preventive measures for cutaneous irAEs (cirAEs). By identifying risk factors, recognizing early signs and implementing preventive strategies, healthcare professionals can significantly mitigate the severity of irAEs, thereby improving patient outcomes and quality of life.