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Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity

Yanqiong Zhang, Chunxia Shi, Danmei Zhang, Luyi Zhang, Lu-Wen Wang, Zuojiong Gong

2023Journal of Integrative Medicine31 citationsDOI

Topics & Concepts

GPX4GlutathioneSulforaphaneChemistryPharmacologyDownregulation and upregulationHDAC6Liver injuryViability assayGlutathione peroxidaseHistone deacetylaseCancer researchMedicineBiochemistryIn vitroEnzymeHistoneGeneFerroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stressSulfur Compounds in Biology
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity | Litcius