Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis
Elena P. Sorokin, Nicolas Basty, Brandon Whitcher, Yi Liu, Jimmy D. Bell, Robert L. Cohen, Madeleine Cule, E. Louise Thomas
Topics & Concepts
SpleenHereditary spherocytosisBiologyPopulationAlleleReticulocyteGeneticsHepcidinImmunologyPhysiologyGeneMedicineMessenger RNAInflammationEnvironmental healthHemoglobinopathies and Related DisordersIron Metabolism and DisordersErythrocyte Function and Pathophysiology