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Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis

Huiwen Yuan, Ningning Zhou, Jie Li, Xiaoning Li, Kailiang Zhou, Jianjun Qi

2025International Immunopharmacology15 citationsDOI

Topics & Concepts

InflammasomePyroptosisOxidative stressChemistryInflammationFibrosisLiver injuryFatty liverPeptideHepatic stellate cellIn vitroPharmacologyReceptorIn vivoCancer researchSteatosisAlanineLiver diseaseCell biologyBiochemistryCaspase 1CytokineLiver fibrosisNecrosisReactive oxygen speciesHemopexinSignal transductionOxidative phosphorylationChronic liver diseaseGlutathioneInflammasome and immune disordersLiver Disease Diagnosis and TreatmentLiver Diseases and Immunity
Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis | Litcius