Litcius/Paper detail

Medicinal Chemistry of Drugs with <i>N</i>-Oxide Functionalities

Michelle Kobus, Timo Friedrich, Eilika Zorn, Nils Burmeister, Wolfgang Maison

2024Journal of Medicinal Chemistry69 citationsDOIOpen Access PDF

Abstract

-oxides in the biomedical field and explains the basic molecular mechanisms responsible for their biological activity.

Topics & Concepts

ChemistryCombinatorial chemistryOxideProdrugNanotechnologyMembrane permeabilityMembraneOrganic chemistryBiochemistryMaterials scienceEicosanoids and Hypertension PharmacologyMicrobial metabolism and enzyme functionNitric Oxide and Endothelin Effects