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Design, synthesis and biological evaluation of novel thiohydantoin derivatives as antiproliferative agents: A combined experimental and theoretical assessments

Mostafa M. Elbadawi, Ahmed I. Khodair, Mohamed K. Awad, Shaymaa E. Kassab, Mohammed T. Elsaady, Khaled R.A. Abdellatif

2021Journal of Molecular Structure29 citationsDOI

Topics & Concepts

ChemistryCytotoxicityDocking (animal)IC50StereochemistryIn vitroCell cultureCytotoxic T cellFibroblastMCF-7Combinatorial chemistryCancer cellHuman breastBiochemistryCancerNursingInternal medicineGeneticsBiologyMedicineSynthesis of heterocyclic compoundsChemical synthesis and pharmacological studiesSynthesis and biological activity
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as antiproliferative agents: A combined experimental and theoretical assessments | Litcius