MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1
Jin Zhang, Xuelei Wang, Jiang Huajun, Fan Yang, Yu Du, Li Wang, Bin Hong
Topics & Concepts
Cholesterol 7 alpha-hydroxylaseFOXO1Bile acidmicroRNAFarnesoid X receptorDownregulation and upregulationBiologyTranscriptional regulationChemistryProtein kinase BGene expressionSignal transductionEndocrinologyCell biologyBiochemistryGeneTranscription factorNuclear receptorFOXO transcription factor regulationMicroRNA in disease regulationFerroptosis and cancer prognosis