Natural alternative heme-environments allow efficient peroxygenase activity by cytochrome P450 monooxygenases
Ana C. Ebrecht, Martha S. Smit, Diederik J. Opperman
Abstract
Mild oxyfunctionalization reactions driven by hydrogen peroxide using cytochrome P450 monooxygenases with alternative heme environments.
Topics & Concepts
MonooxygenaseHemeCytochrome P450ChemistryHemeproteinCytochromeHydrogen peroxideBiochemistryEnzymePharmacogenetics and Drug MetabolismMetal-Catalyzed Oxygenation MechanismsSynthesis and Catalytic Reactions