Dithiocarbamate-based novel anti-histaminic agents: synthesis, characterization, crystal structure and thermal study
Anupam Singh, R. Kumar, Riya Patel, Trishna, Ram Nayan Gautam, M.K. Bharty, Lal Bahadur Prasad
Abstract
animal model. The result shows that these synthesized compounds have antihistaminic potential to inhibit clonidine-induced catalepsy and may be targeted for different allergic conditions. Complex 3 showed maximum reduction in clonidine-induced catalepsy after 180 minutes of treatment when compared with the induced control.
Topics & Concepts
DithiocarbamateChemistryCharacterization (materials science)Ligand (biochemistry)MetalCrystal structureStereochemistryCrystallographyMaterials scienceOrganic chemistryNanotechnologyReceptorBiochemistryOrganometallic Compounds Synthesis and CharacterizationSynthesis and Reactivity of Sulfur-Containing CompoundsCrystal structures of chemical compounds