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Regulation of gene expression by alternative polyadenylation in health and disease

Bin Tian, SHAN Yu, Qiang Zhang

2026Nature Reviews Genetics6 citationsDOIOpen Access PDF

Topics & Concepts

BiologyPolyadenylationGeneticsThree prime untranslated regionGeneRegulation of gene expressionGene expressionGene isoformTranscriptomeUntranslated regionAlternative splicingRNA-binding proteinmicroRNARNACell biologyTranscription (linguistics)DiseaseMessenger RNAHuman geneticsTranscription factorGene knockdownRegulatory sequenceMutationHuman genomeGene regulatory networkRNA splicingAlleleComputational biologyRNA interferenceRegulator geneCellular differentiationCell typeRNA Research and SplicingBiochemical Acid Research StudiesRNA modifications and cancer
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