Novel AAV variants with improved tropism for human Schwann cells
Matthieu Drouyer, Tak‐Ho Chu, Elodie Labit, Florencia Haase, Renina Gale Navarro, Deborah Nazareth, Nicole L. Rosin, Jessica Merjane, Suzanne Scott, Marti Cabanes‐Creus, Adrian Westhaus, Erhua Zhu, Rajiv Midha, Ian E. Alexander, Jeff Biernaskie, Samantha L. Ginn, Leszek Lisowski
Abstract
models of hSCs. These novel AAV capsids will serve as valuable research tools, forming the basis for therapeutic solutions for both SC-related disorders or peripheral nervous system injury.
Topics & Concepts
TropismVirologyBiologyComputational biologyVirusVirus-based gene therapy researchHerpesvirus Infections and TreatmentsOrgan and Tissue Transplantation Research